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Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Erythematosus (SLE ... Erythematosus #SLE ... Signs #Symptoms #Rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... and Immunologic ... Criteria CLINICAL ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... 40, F:M 9:1 • Clinical ... are evocative of SLE ... Cytopenia: Common • Immunologic ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... drug-dependent) • Immunologic ... 40, F:M 9:1 • Clinical ... Cytopenia: Common • Immunologic ... comparison #table #rheumatology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Pathogenesis and clinical ... Erythematosus (SLE ... HypersensitivityReaction #Allergy #Immunology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... lupus nephritis Immunologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... is clinically suspected ... higly specific for SLE ... erythematosus #diagnosis #rheumatology
Ascites, pericardial effusion, and left pleural effusion on subcostal 4-chamber POCUS echocardiogram

Subcostal window in SLE patient.
-chamber POCUS echocardiogram ... Subcostal window in SLE ... effusion #s4c #POCUS #echocardiogram ... #POCUS #clinical
Papillary Muscle Rupture on POCUS

See the "cracking whip"?  This is what papillary muscle rupture looks
Rupture on POCUS See ... Muscle #Rupture #Echocardiogram ... #POCUS #Clinical
Ruptured Chordae Tendineae on POCUS Echocardiogram
 
Many underlying causes, not limited to: MVP, subacute endocarditis, connective
Tendineae on POCUS Echocardiogram ... for MR when you see ... Tendineae #POCUS #Echocardiogram ... #Ultrasound #Clinical