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diagnosis differential infectiousdiseases management oncology algorithm aids chronic dermatology hiv leukemia lymphocytic pathophysiology syndrome vasculitis workup allergy american antimda5 antimda5dm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... Myelofibrosis Infectious ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Lymphocytic Leukemia (CBC ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... weeks without infection ... Lymphocytosis on CBC ... surface molecules: CD5 ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... salmonella, ...), Parasites ... lymphoma, B-cell ... Drugs, Unknown cause ... treatment #summary #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
-cell count is less ... present in 15% of cases ... -cell count more ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Diagnosis Algorithm Infectious ... Viral (EBV) • Parasitic ... Disease • Sickle Cell ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... decreased PLT count: CBC ... not required in all ... or if a primary hematologic ... #Workup #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Decreased CD4 ... + and CD8+ T cell ... +/CD8+ ratio are ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
T-cell lymphopenia ... T-cell count of ... myelodysplasia) • Infections ... ICL #diagnosis #hematology ... #Differential #Causes
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Cr >2 mg/dL or CC ... Causes of false- ... amyloidosis Other causes ... diseases, CML, ... MGUS #diagnosis #hematology
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