30 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Leukemia (CBC with ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... Lymphocytosis on CBC ... surface molecules: CD5 ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... pain, bleeding, infections ... bruising, bleeding, infection ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... Vmphocytosis on routine CBC ... Complications: 1) Infection ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... Myelofibrosis Infectious ... Diagnosis #Algorithm #Causes ... #Hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
T-cell count of ... mL or 20% total lymphocyte ... myelodysplasia) • Infections ... ICL #diagnosis #hematology ... #Differential #Causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... salmonella, ...), Parasites ... lymphoma, B-cell ... Drugs, Unknown cause ... treatment #summary #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
-cell count is less ... present in 15% of cases ... -cell count more ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... Diagnosis Algorithm Infectious ... Viral (EBV) • Parasitic ... Disease • Sickle Cell ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... decreased PLT count: CBC ... not required in all ... or if a primary hematologic ... #Workup #hematology