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autoantibodies differential antinuclear cold connectivetissuediseases ctild definition druginduced endocarditis erythematosus hematology ild infarction infective inflammatory lungdisease management marantic myocardial myopathies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology # ... Associations
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... -15% If SLE is clinically ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Workup: - ANA ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... pain, such as MI ... #Presentation #comparison ... #Table #Diagnosis
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 Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
clinical associations ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Differentiating type-I vs. type-II MI Sorting this out is difficult, often relying heavily on clinical judgement. A key
relying heavily on clinical ... The table below ... #Diagnosis #Myocardial ... Definition #NSTEMI #Comparison ... #Table
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Anti-MDA5, anti-Mi ... Pattern: Proximal and ... #differential #diagnosis ... #comparison #rheumatology ... #table
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
diagnosis can only ... heart valves • MRI ... often seen • MRI ... #Endocarditis #comparison ... #table
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... sequestration and ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
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