16 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... ANA - Non-specific ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
clinical associations ... duration of symptoms ... angioedema Other symptoms ... #rheumatology # ... comparison #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... searched for when ANA ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Differentiating type-I vs. type-II MI

Sorting this out is difficult, often relying heavily on clinical judgement.

A key
type-I vs. type-II MI ... If the same symptoms ... The table below ... #Diagnosis #Myocardial ... NSTEMI #Comparison #Table
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... pain, such as MI ... #Pericarditis #Symptoms ... Presentation #comparison #Table ... #Diagnosis
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... diagnosis can only ... heart valves • MRI ... often seen • MRI ... #table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... Pattern: Proximal and ... #differential #diagnosis ... #comparison #rheumatology ... #table
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... and Management ... caucasian • Symptoms ... R-G or B-Y • MRI ... Management #treatment #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Asia • HLA-B51 association ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... management #signs #symptoms ... #rheumatology #