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diagnosis comparison differential lupus management antibodies antinuclear antinxp2 antinxp2dm autoimmune cold dermatology dermatomyositis druginduced erythematosus inflammatory myopathies myopathy myositis sle
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... #Associations # ... #table #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Lupus (SLE): ANA ... , Others: SRP, Mi ... diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... with auto-immune diseases ... #Antinuclear #autoantibodies ... erythematosus #diagnosis #rheumatology ... #table #ANA
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
to 50X ULN • Autoantibodies ... Anti-MDA5, anti-Mi ... Pattern: Proximal and ... diagnosis #comparison #rheumatology ... #table
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
of life Causes and ... clinical associations ... liquids The onset and ... Urticaria #diagnosis #rheumatology ... #comparison #table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... of autoantibodies ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... -1 antibodies (ANA ... (also seen in association ... Mechanic's hands Autoantibodies ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
severe weakness, and ... without these autoantibodies ... had more severe disease ... • Myoglobin Association ... diagnosis #management #rheumatology
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