12 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... common in SLE, autoimmune ... microsomal) - Autoimmune ... Autoantibodies #Associations ... #table #rheumatology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Differential Diagnosis Table ... (48-70%) Cold AHA ... Cold Agglutinin Disease ... #hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
of life Causes and ... clinical associations ... Autoimmune diseases ... Urticaria #diagnosis #rheumatology ... #comparison #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... with disease activity ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... focal lesions on MRI ... chain deposition disease ... autoimmune diseases ... MGUS #diagnosis #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
early localized disease ... well-described associations ... called "Bazin's disease ... Classic association ... Erythemas #comparison #table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... exclusion Necrotizing Autoimmune ... Pattern: Proximal and ... diagnosis #comparison #rheumatology ... #table
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Predisposing conditions: Autoimmune ... heart valves • MRI ... often seen • MRI ... - Infectious Diseases ... Marantic #diagnosis #table
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Myositis Any ... that occurs in association ... features of another autoimmune ... connective tissue disease ... IIMs #diagnosis #rheumatology