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autoantibodies comparison differential dermatology antibodies antimda5 antimda5dm antinuclear antinxp2 antinxp2dm autoimmune cold connectivetissuediseases ctild erythematosus ild inflammatory lungdisease lupus management
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Polymyositis / Dermatomyositis ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
DM/PM : dermatomyositis ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... with auto-immune diseases ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
clinical associations ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... severity of the disease ... frequently described Association ... #rheumatology # ... dermatology #diagnosis
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... Anti-MDA5, anti-Mi ... Pattern: Proximal and ... #comparison #rheumatology ... #table
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... • Myoglobin Association ... : • ILD was diagnosed ... #diagnosis #management ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... • Anti-NXP2 (ANA ... (also seen in association ... Myositis #Myopathy #rheumatology
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