7 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... ANA - Non-specific ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
inflammatory myopathy ... that occurs in association ... connective tissue disease ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... searched for when ANA ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
of life Causes and ... clinical associations ... liquids The onset and ... Urticaria #diagnosis #rheumatology ... #comparison #table
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Benefits: ↓ Disease ... Prolonged QTc (association ... Neuro-muscular: vacuolar myopathy ... Worsening of other diseases ... #sideeffects #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... -1 antibodies (ANA ... (also seen in association ... syndrome • If myopathy ... #rheumatology #