13 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... ANA - Non-specific ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... with disease activity ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
of life Causes and ... clinical associations ... liquids The onset and ... Urticaria #diagnosis #rheumatology ... #comparison #table
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
NOT interpret MRI ... diagnosis: • Inflammatory ... diffuse chondral disease ... Has blooming on MRI ... diagnosis #msk #rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... Pattern: Proximal and ... diagnosis #comparison #rheumatology ... #table
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... Asia • HLA-B51 association ... (25-75%): Inflammatory ... signs #symptoms #rheumatology ... #disease
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
alveolitis, ear and ... thromboembolic disease ... /or 2) Inflammatory ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Myositis Any ... that occurs in association ... connective tissue disease ... muscle biopsy, and ... IIMs #diagnosis #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic inflammatory ... often a nonerosive inflammatory ... - MRI: inflammation ... skin disease. ... SAPHO #Syndrome #Rheumatology