11 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... others (RNP, aPL antibodies ... , Others: SRP, Mi ... diagnosis #associations ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... Goodpasture's syndrome #Autoantibodies ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific Antibodies ... , TIF1y, NXP2, Mi ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... Associated Features: Diagnosis ... #differential #diagnosis ... #comparison #rheumatology ... #table
Pemphigus Vulgaris vs Bullous Pemphigoid - Comparison Table
Pemphigus Vulgaris
 • Epidemiology: Average age 40-60
 • Time
Pemphigoid - Comparison Table ... , relapsing • Symptoms ... : Autoantibodies ... , relapsing • Symptoms ... Pemphigoid #Comparison #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Erythematosus - Diagnosis ... SLE-Related Auto-Antibodies ... #autoantibodies ... #signs #symptoms ... #differential #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... months) and of autoantibodies ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... pain, such as MI ... #Pericarditis #Symptoms ... Presentation #comparison #Table ... #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Rheumatology