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autoantibodies comparison differential management antinuclear arthritis associations biliary cbd cholangiocarcinoma dilated endocarditis erythematosus gout gouty hematology hemeonc hemophagocytic hlh infective
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... , TIF1y, NXP2, Mi ... #MSAs #clinical ... #diagnosis #rheumatology ... #table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... Pattern: Proximal and ... #comparison #rheumatology ... #table
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
or clinical history ... surgeon had a clinical ... /or mass ... #clinical #Radiology ... #rheumatology
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
diagnosis can only ... heart valves • MRI ... features: Mobile mass ... often seen • MRI ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... -15% If SLE is clinically ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... out compressive myelopathies ... Antiamphiphysin antibodies
Dilated Common Bile Duct on POCUS 50's yo patient with RUQ abd pain. Vitals stable/afebrile. Labs: WBC
Vitals stable/afebrile ... MRI/MRCP. ... Found to have mass ... Diagnosed with cholangiocarcinoma ... POCUS #ultrasound #clinical
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 Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... (often termed MAS-HLH ... Clinical Presentation ... inhibitors, anti-IFN-γ antibodies ... #Management #Hematology
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