11 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... , TIF1y, NXP2, Mi ... #Myositis #Specific ... clinical #diagnosis #rheumatology ... #table
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #associations #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Associations ANA - Non-specific ... diseases #diagnosis #table ... #rheumatology #
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
60-70% Highly specific ... 10-30% Highly specific ... Considered higly specific ... erythematosus #diagnosis #rheumatology ... #table #ANA
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
features that are specific ... heart valves • MRI ... often seen • MRI ... Marantic #diagnosis #table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... diagnosis #comparison #rheumatology ... #table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Cancer-treatment specific ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Imaging Modalities for Renal Calculus

AXR. KUB
 - Good far calcium-containing stones useful when limited radiation dose
sensitive and specific ... obstruction - Able ... Combination of above MRI
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... pain, such as MI ... Presentation #comparison #Table
Relevance of diagnostic investigations in uveitis 

Chest CT-scan - Bronchoscopy - LSGB - Cerebral MRI -
LSGB - Cerebral MRI ... investigations or of specific ... Workup #Yield #Rheumatology