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hematology management adjusted age algorithm bandemia blood causes coagulation ddimer dic differentiation disorders disseminated intravascular markers neutrophil oncology syndrome thromboticthrombocytopenicpurpura
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
D-dimer Plasma ... D-dimer is a product ... #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... #hematology #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Acute • Myloid (AML ... bcr-able (+) ↑ WBC ... #Diagnosis #Algorithm
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... Diagnosis: • ... #Bandemia #differential ... #WBC #CBC #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Elevated D-Dimer ... protein C and S Pathophysiology ... • PTT: ↑ • D-Dimer ... hydration • RBC ... #Coagulation #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... products or D-dimer ... from ischemia WBC ... count and differential ... #Workup #Hematology
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