29 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... delayed puberty -> Infertility ... #PraderWilli #Syndrome ... #genetics #pathophysiology
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... therapy of ALL, AML ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal Syndromes ... and Mimics - Differential ... Antiphospholipid Syndrome ... in APL - Cardiac ... #Mimics #Differential
Patterns of Diseases on MRI FLAIR - Differential Diagnosis
ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
on MRI FLAIR - Differential ... Tumefactive, NMO, PRES, PML ... Disease, Susac Syndrome ... Diseases #MRI #Differential
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... - Refeeding Syndrome ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome ... #Causes #Differential
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
of Seizures - Differential ... vasoconstriction syndrome ... Neurocysticercosis, PML ... Prophyria #Seizures #Differential
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag Syndrome ... Purple #Urine #Bag #Syndrome ... #PUBS #pathophysiology ... clinical #photo #differential
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... hypereosinophilic syndrome ... Hyper-lgE (Job) syndrome ... ), Heme malig (AML ... #Eosinophilia #Differential