43 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... / Symptoms: - ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
liver or kidney disease ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... PBC if 2/3 criteria
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Bladder retention -> Primarily ... hemicord lesion -> Primarily ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Criteria for Guillain ... , Mild sensory symptoms ... or signs, Cranial ... #diagnosis #criteria ... #neurology #neuropathy
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Signs and symptoms ... criteria for MS ... Progressive MS • Primary
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... reflexes) • Urinary ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
mainly AQP4-lgG disease ... (AQP4-lgG disease ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
arrest, Kounis syndrome ... vaginal bleeding and urinary ... #anaphylaxis #signs ... #symptoms #diagnosis ... #criteria #allergy