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diagnosis differential hypercalcemia management signs symptoms algorithm treatment hypocalcemia parathyroid pediatrics peds pth 21hydroxylasedeficiency 21ohd acromegaly associated bulimianervosa calcitriol clinical
Hormonal Regulation of the Blood Calcium concentration #Calcium #Regulation #Parathyroid #Calcitonin #Calcitriol #PTH #Endocrinology #Pathophysiology #Hormones
Regulation of the Blood Calcium ... concentration #Calcium ... #Parathyroid #Calcitonin ... Calcitriol #PTH #Endocrinology ... #Pathophysiology
Effects of Parathyroid hormone (PTH) and Calcitonin on Calcium and Phosphate Metabolism #Parathyroid #hormone #PTH #Calcitonin #phosphate
hormone (PTH) and Calcitonin ... on Calcium and ... #hormone #PTH #Calcitonin ... phosphate #metabolism #pathophysiology ... #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... delayed puberty -> Infertility ... #PraderWilli #Syndrome ... #genetics #pathophysiology
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... )-alkali syndrome ... Hypercalcemia #Causes ... differential #diagnosis #calcium ... #high #endocrinology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hyperparathyroidism Genetic ... Other humoral syndromes ... Hypercalcemia #Causes ... Differential #Diagnosis #Endocrinology
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 21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... high WBC count cause ... hyperviscosity syndrome ... : • Pathophysiology
Causes of Hypercalcemia due to increased Vitamin D levels • The BIG 3:
Causes of Hypercalcemia ... Paraffin-associated granuloma • Genetic ... : Williams syndrome ... Hypercalcemia #VitaminD #causes ... differential #diagnosis #endocrinology
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
low circulating calcium ... hypocalcemia - Genetic ... defects in calcium-sensing ... Malabsorption syndrome ... Differential #Diagnosis #Endocrinology
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 Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... • Milk-alkali syndrome ... Hypercalcemia #Causes ... #endocrinology
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