28 results
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Parathyroid Hormone (PTH ... - Net Effect Hypercalcemia ... Parathyroid #Hormone #PTH ... #Phosphorus #pathophysiology ... #endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
histoplasmosis) • Milk (calcium ... )-alkali syndrome ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... - Calcium Sequestration ... - DiGeorge Syndrome ... Diagnosis #Management #endocrinology ... #differential #
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... Determine whether PTH-dependent ... Diagnosis #algorithm #endocrinology ... #calcium
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Serum levels of PTH ... dihydroxyvitamin D can help differentiate ... Hypoparathyroidism - Calcium-sensing ... Hyperparathyroidism #Diagnosis #Endocrinology ... #Differential
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... Algorithm Elevated PTH ... Low PTH: • Elevated ... Bony Mets - Calcium ... Algorithm #causes #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... Poisoning #Hypocalcemia ... #Differential # ... Algorithm #Phosphate #endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
, ↑Calcium, ↑Vitamin ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Differential Diagnosis ... Autosomal Dominant Calcium ... Malignancy • PTH-Related ... #Differential # ... Diagnosis #Algorithm #Endocrinology
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Hyperparathyroidism • Hypercalcemia ... Various Pituitary path ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology