78 results
Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... @NEPHKIDS1 #Hypocalcemia ... #differential #diagnosis ... #endocrinology ... #causes #calcium
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
PTH) Effect in Calcium ... and Phosphorus Calcium ... - Net Effect Hypercalcemia ... #Phosphorus #pathophysiology ... #endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
histoplasmosis) • Milk (calcium ... )-alkali syndrome ... #differential #diagnosis ... #calcium #high ... #endocrinology
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Hypocalcemia Laboratory ... disorders causing hypocalcemia ... Hypoparathyroidism - Calcium-sensing ... Hyperparathyroidism #Diagnosis ... #Endocrinology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... Calcium-containing ... Calcitriol improves hypocalcaemia ... the first-line treatments ... #Pharmacology #Pathophysiology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... - Calcium Sequestration ... - DiGeorge Syndrome ... #Diagnosis #Management ... #endocrinology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... 4.6 mg/dL • Calcium ... • Hypocalcemia ... - Calcium gluconate ... #TLS #diagnosis
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential Diagnosis ... #Differential #Diagnosis ... #algorithm #endocrinology ... #calcium
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Neoplasias (MEN syndromes ... Hyperparathyroidism • Hypercalcemia ... Hyperparathyroidism • Hypercalcemia ... #Differential #Endocrinology ... Classification #Diagnosis
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Diagnosis Algorithm ... Phenytoin, Nephrotic Syndrome ... #Differential #Diagnosis ... Algorithm #Phosphate #endocrinology