33 results
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Parathyroid hormone–dependent ... hyperparathyroidism Genetic ... ) Parathyroid hormone–independent ... - Parathyroid hormone–related ... Differential #Diagnosis #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
common), growth hormone ... ) the anterior hormones ... most essential hormones ... the order the hormones ... Loss of pituitary hormones
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... action of thyroid hormones ... receptors for thyroid hormone ... reflex hammer, caused ... video #neurology #endocrinology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... over-secretion of growth hormone ... Acromegaly #Signs #Symptoms ... #Diagnosis #Endocrinology
Abnormal Lipid Profiles - Differential Diagnosis Algorithm

Increased Cholesterol and Triglycerides 
 - Genetic Causes
Triglycerides - Genetic ... • Nephrotic Syndrome ... Increased LDL Genetic ... • Nephrotic Syndrome ... Pregnancy, Hormone
Weight Gain / Obesity  - Differential Diagnosis Algorithm
Decreased Expenditure:
 • Sedentary Lifestyle
 • Smoking Cessation
• Cushing's Syndrome ... Hypothalamic Obesity Genetic ... Iatrogenic: • Drugs/Hormones ... Diagnosis #Algorithm #endocrinology ... #causes
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... • Other rare causes ... Carpal Tunnel Syndrome ... diagnosis #signs #symptoms ... #endocrinology
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Polycystic Ovarian Syndrome ... • Cushing's Syndrome ... Tumor Low Serum Hormone ... Diagnosis #Algorithm #endocrinology ... #causes
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... delayed puberty -> Infertility ... #genetics #pathophysiology