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hematology management monoclonal differential disease multiplemyeloma agglutinin anemia antiphospholipid apls biopsy bleeding cancer capillary clarksons cold complications disorders eosinophilia eosinophils
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS) Mayo Clinic Risk Stratification Model. CBC,
Suggested algorithm ... significance (MGUS ... ) Mayo Clinic Risk ... #algorithm #diagnosis ... #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
Suggested algorithm ... with monoclonal gammopathy ... whom there are no clinical ... algorithm #diagnosis ... #management #hematology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #management #algorithm
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
of Monoclonal Gammopathy ... Significance (MGUS ... rituximab (in clinical ... Complications #diagnosis ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... IgM monoclonal gammopathy ... significance (MGUS ... hemolytic #anemia #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • MGUS ... changes (POEMS syndrome ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Relapsing-remitting course +++ Clinical ... Monoclonal gammopathy ... #diagnosis #management ... timeline #treatment #rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup Algorithm ... - 1 or more clinical ... Antiphospholipid #Syndrome ... #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Marfan syndrome, ... History #peds #pediatrics ... #diagnosis #hematology
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