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diagnosis hepatology management algorithm differential causes injury syndrome acute chronic cirrhosis hepatocellular hepatopulmonary pharmacology rheumatology table acidosis aclf adultonset aih
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... disease, liver ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Toxic: Alcohol, Medication ... Syndrome, Celiac Disease ... , Infiltrative Disease ... GVHD • Toxic: Medication ... Acute #algorithm #hepatology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
unresponsive to treatment ... • Elevated liver ... autoimmune thyroiditis, hepatitis ... Autoimmune • CVID • Medications ... Diagnosis #Algorithm #gastroenterology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... , HSV, VZV • Medications ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Transaminitis #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... disease, Hepatic ... ascites), Chronic hepatitis ... • Autoimmune hepatitis
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Supportive with treatment ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... mg/dL) or acute liver ... failure #HepatitisB ... #hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Anticoagulant Medications ... ) • Advanced Liver ... Disease - Alcohol ... , Viral hepatitis ... comparison #diagnosis #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... hepatomegaly, hepatitis ... • Pulmonary: ... diagnosis #management #treatment ... #rheumatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... hepatocellular pattern of liver ... Management - Strong indications ... regarding need for treatment
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