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diagnosis management differential erythematosus systemic comparison druginduced summary syndrome table vasculitis activation ana antibodies antinuclear associations cancer cerebritis classification cns
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... • Specific for SLE ... Treatment: • ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... rheumatoid arthritis SLE ... : systemic lupus ... Comparison #Table #Pulmonary ... #Rheumatology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Reaction to Medications ... #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... erythematosus (SLE ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... Puncture, EEG Treatment ... Erythematosus #SLE ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Erythematosus (SLE ... life-threatening • Treatment ... Evolution: Chronic disease ... #table #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... With associated pulmonary ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm ... #rheumatology
Holistic Management of Systemic Lupus • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
Management of Systemic Lupus ... • Pregnancy & fertility ... #holistic #SLE ... Erythematosus #management #treatment ... #rheumatology
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