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Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
diseases that cause ... Achalasia has an insidious ... Chagas disease) Clinical ... Three clinical features ... Achalasia #diagnosis #management
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
Causes of Hypernatremia ... Central diabetes insipidus ... Nephrogenic diabetes insipidus ... Differential #Diagnosis #Causes
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup Step #1 - Consider the history Step #2 - Assess
Algorithm - Diabetes Insipidus ... Hypernatremia #Management ... Sodium #nephrology #insipidus
Polyuria - Differential Diagnosis Algorithm Urine Output > 3L /day Water Diuresis (Urine Osm <100 mOsm/kg) • Primary
Central Diabetes Insipidus ... Nephrogenic Diabetes Insipidus ... Diagnosis #Algorithm #causes
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes Insipidus ... neurogenic diabetes insipidus ... Nephrogenic diabetes insipidus ... uropathy, Metabolic causes ... #Diabetes #Insipidus
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Central Diabetes Insipidus ... Nephrogenic Diabetes Insipidus ... Diagnosis #Table #Causes
Causes of Polyuria - Differential Diagnosis Algorithm Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min) Osmotic
Causes of Polyuria ... Central Diabetes Insipidus ... Nephrogenic Diabetes Insipidus ... Diagnosis #Algorithm #Causes
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Causes of Hypernatremia ... kg • Diabetes Insipidus ... Diagnosis #Algorithm #Causes
Causes of Enuresis - Differential Diagnosis Algorithm Primary Nocturnal Enuresis (Urinary Control Never Achieved) • Delayed Maturation
Causes of Enuresis ... Other (Diabetes Insipidus ... Diagnosis #Algorithm #Causes
Hypothalamus Anatomy and Hypothalamic Nuclei • Anterior hypothalamic nucleus - Body temperature, thermal regulation (heat dissipation),
oxytocin, destruction causes ... diabetes insipidus ... regulation, destruction causes
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