35 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... common • Imaging: CXR ... organ dysfuxtion, ICU ... • Supportive Care
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... - ACS, AKI, acute ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Pathogenesis and Clinical ... mood - Primary treatment ... #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
associated with acute ... Pathophysiology: ... : While it's a rare ... is not diagnostic ... peritonitis #IM #FM #ICU
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... Signs of poor perfusion ... Signs of congestion ... Cardiac cath if acute ... #criticalcare #icu
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Pathogenesis and clinical ... tendon ruptures are ... warriors") • Acute ... TendonRupture #diagnosis ... #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... At least 3 of (Acute ... fluid balance, and CXR ... Reactions #hematology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... #management #treatment
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ICU ... ED triage notes are ... something has acutely ... get an EKG and CXR ... Pearls #Checklist #diagnosis
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Blood cultures • CXR ... early disease) • CXR ... Clindamycin in case