21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
risk-stratification • Risks: infection ... transformation to acute ... Conservative/supportive care ... only curative treatment ... #hematology #oncology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
therapies in critical care ... steroids to treat infectious ... ventilation, ARDS acute ... #Pharmacology # ... Management #Treatment
Pharmacotherapy for Migraine Prophylaxis 

Who is indicated for migraine prophylaxis? Patients who experience more than 3
despite appropriate acute ... treatment, or those ... contraindications to acute ... #Medications #Table ... #Pharmacology #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Presentation: Subacute-Acute ... : DAH, acute febrile ... Differential Diagnosis: Infection ... , Anaphylaxis, Acute ... #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... megaloblastic anemia Treatment ... • Supportive care ... progress to MDS or acute ... #hematology
Sexually Transmitted Infections - Common Outpatient Treatments 
Chlamydia 
 - Azithromycin 1 g PO once
Sexually Transmitted Infections ... Common Outpatient Treatments ... of ambulatory care ... conditions including acute ... #Management #Pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs are substrates ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... presents as an acute ... • Bicytopenia Treatment ... : • Infection ... #hematology
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Disease Note: Treatment ... patients with acute ... Preferred Therapy for Acute ... opportunistic #infections ... #HIVAIDS #pharmacology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
presents with acute ... pulmonary symptoms • Rheumatologic ... to 12 weeks for acute ... Chronic, subacute to acute ... Coccidioidomycosis Symptoms: • Acute