12 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... Lymphadenopathy AML (Acute ... Blasts APML (Acute ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
large numbers and are ... thrombocytopenia • AIHA ... microglobulin Treatment ... ’s lymphoma or acute ... workup #oncology #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... months without treatment ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... Consider stem cell ... • Supportive care ... progress to MDS or acute ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute ... Conservative/supportive care ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... If suspected, AIH ... Management - Strong indications ... regarding need for treatment ... Diagnosis #Management #Hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
, smudge cells are ... cytopenias (ITP, AIHA ... low-risk disease • Indications ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Indications Treatment ... ) • Use of B-cell ... immunosuppression • Acute ... > 3 mg/dL) or acute ... #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
~10% - B-Cell ... Responsive to Treatment ... Treated Like Acute ... growth, response to treatment ... pathophysiology #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Induce blast cell ... Presentation: Subacute-Acute ... : DAH, acute febrile ... , Anaphylaxis, Acute ... diagnosis #management #hematology