20 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... Physical Exam Acute ... #PhysicalExam # ... #video #skin #dermatology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... Lymphadenopathy AML (Acute ... Blasts APML (Acute ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
large numbers and are ... Physical Exam/Signs ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Presentation: Subacute-Acute ... : DAH, acute febrile ... , Anaphylaxis, Acute ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute ... Conservative/supportive care ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Consider stem cell ... • Supportive care ... progress to MDS or acute ... management #treatment #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... headache, malaise) → Acute ... ↓Antithrombin Ill ... Support - Critical care
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
tumour B cells are ... ~10% - B-Cell ... Treated Like Acute ... Classification #pathophysiology ... #Hematology #Diagnosis
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Crisis Sickle-cell ... of factors and are ... The underlying pathophysiology ... 2) Aplasia - Acute ... Crisis #Features #Signs
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
associated with HAPE are ... common causes of acute ... • Signs/Symptoms ... • Signs/Symptoms ... Embolism: • Acute