15 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
granules which are ... during an allergic reaction ... translocation • Acute ... thrombocythemia • Acute ... #hematology #basophils
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... lactam antibiotics are ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... • Supportive care ... progress to MDS or acute ... #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... Conservative/supportive care ... #treatment #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... - APLS • Acute ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #rheumatology #
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... Idiosyncratic drug reactions ... Megaloblastic anemia-rare ... Idiosyncratic drug reactions-most ... #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... severity Treatment - Acute ... multidisciplinary care ... #treatment #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... headache, malaise) → Acute ... Support - Critical care ... Liver #Pregnancy #hepatology