21 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
granules which are ... during an allergic reaction ... translocation • Acute ... thrombocythemia • Acute ... #hematology #basophils
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... of acute myeloid ... Dysplastic neutrophils are ... neutrophils #AML #Clinical ... #Hematology #Pathology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... morphologic features are ... features in most cases ... APML #Pathology #Hematology ... #Clinical #Smear
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... transformation to acute ... Conservative/supportive care ... #treatment #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Care TRICC - ... NEJM 1999 - ICU FOCUS ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... Risk factors: Critical ... without other cause ... At least 3 of (Acute ... #hematology #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... severity Treatment - Acute ... Chronic Management ... #treatment #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... headache, malaise) → Acute ... care support, Transfer ... Liver #Pregnancy #hepatology