29 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
granules which are ... during an allergic reaction ... translocation • Acute ... thrombocythemia • Acute ... #hematology #basophils
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute ... Conservative/supportive care ... only curative treatment ... #treatment #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... are asthma, allergy ... , drug reaction, ... glucocorticoid treatment ... Differential #diagnosis #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... - Acute Bleeding ... multidisciplinary care ... #treatment #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... • Supportive care ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... without other cause ... : 33% • Treatment ... At least 3 of (Acute ... #hematology #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema: • Acute ... Non-allergic drug reaction ... inherited disease Acute ... cell-mediated in > 90% of cases ... #management #allergy
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... • SJS/TEN • Acute ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology ... #diagnosis #management