18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Kawasaki, Nephrotic syndrome ... , POEMS • Reaction ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
granules which are ... during an allergic reaction ... Disorders: • Chronic ... translocation • Acute ... Diagnosis #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Conservative/supportive care ... Myelodysplastic #Syndrome ... #treatment #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... severity Treatment - Acute ... Chronic Management ... multidisciplinary care ... #treatment #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... • Acute Hemolytic ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Reaction ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Supportive Care ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... : • Nephrotic syndrome ... Malignancies • Chronic ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... - Symptoms of chronic ... Hepatitis (eg Viral) Management ... AIH #Diagnosis #Management ... #Hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... When Cancer Cells are ... #Leukemia #Hematology