19 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... - If present, are ... • Immunologic Workup ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... transformation to acute ... leukemia Management ... Conservative/supportive care ... #treatment #hematology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... - Cuteanous: acute ... to very rare: due ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
• Supportive care ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... infections (bacterial), acute ... • Acute = Viral ... Joint #Pain #MSK #rheumatology ... #approach #workup
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... severity Treatment - Acute ... Chronic Management ... multidisciplinary care ... #treatment #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Presentation: Subacute-Acute ... : DAH, acute febrile ... , Anaphylaxis, Acute ... APML #diagnosis #management ... #hematology #oncology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
hypergammaglobulinemia, ↑ acute ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
It is rare in presentation ... presents as an acute ... insulting agent are ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology