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The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
- Lung cysts (LAM ... on the basis of HRCT ... Diagnosis #Radiology #Pulmonary ... #CTChest #LowAttenuation ... #SignetRing #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
(centrilobular emphysema ... bronchiolitis (RB-ILD ... is seen in: - UIP ... #HRCT #ChestCT ... #Upper #Lower #RadiologyAssistant
UIP with honeycombing (left) and chronic HP (right)
Differential diagnosis of Hypersensitivity Pneumonitis.
Subacute stage:
- RB-ILD: seen in
centrilobular emphysema ... show very similar HRCT ... fibrotic changes are ... Diagnosis #Radiology #CTChest ... #RadiologyAssistant
Acute interstitial pneumonia (AIP, earlier named Hamman Rich Pneumonitis) is a rare idiopathic lung disease characterized
Acute interstitial ... aswell as the HRCT ... from acute respiratory ... Clinical #Radiology #CTChest ... #ILD #RadiologyAssistant
Basic Interpretation
A structured approach to interpretation of HRCT involves the following questions:
What is the dominant HR-pattern:
reticular
nodular
high
low attenuation (emphysema ... Diagnosis #Radiology #Pulmonary ... #HRCT #CTChest ... Interpretation #Algorithm #ILD ... #RadiologyAssistant
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
morphologic findings on HRCT ... Diagnosis #Radiology #Pulmonary ... #CTChest #Idiopathic ... IdiopathicInterstitialPneumonia #ILD ... #Findings #RadiologyAssistant
On the left a typical case of panlobular emphysema.
There is uniform destruction of the underlying architecture
Pulmonary vessels ... the other hand, mild ... difficult to detect on HRCT ... Clinical #Radiology #CTChest ... PanlobularEmphysema #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
On HRCT there are ... On a Chest X-Ray ... in many cases UIP ... Diagnosis #Radiology #Pulmonary ... #Differential #RadiologyAssistant
Lymphocytic interstitial pneumonitis or LIP is uncommon, being seen mainly in patients with autoimmune disease, particularly
Symptoms are nonspecific ... underlying disease HRCT ... findings are usually ... Clinical #Radiology #CTChest ... #ILD #RadiologyAssistant
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Primary - Other (Rare ... Lymphangioleiomyomatosis (LAM ... ), • Pulmonary ... , Beomycin • Acute ... Lung #Diseases #ILD