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liver hematology lfts aflp algorithm hepatitis injury management obstetrics pathophysiology pregnancy table apml basophilia basophils bleeding bruising causes chemistry classification
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Diagnosis Framework ... Hepatopathy • Acute ... #Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 20x normal - Acute ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Etiology of Acute Liver Failure – bolded entities are most likely to cause AST/ALT in the
Etiology of Acute ... in the 1000s #Diagnosis ... #Acute #LiverFailure ... #Transaminitis ... #Differential
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... granules which are ... translocation • Acute ... thrombocythemia • Acute
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... Cirrhosis: > 1 • Acute ... Hepatology #transaminitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Presentation: Subacute-Acute ... : DAH, acute febrile ... initiation • Differential ... , Anaphylaxis, Acute ... • Supportive Care
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... infiltration) Differential ... Support - Critical care ... Liver #Pregnancy #hepatology
When assessing a patient with acute dyspnea during or shortly following a transfusion, it is challenging
a patient with acute ... challenging to differentiate ... and wheeze, but are ... #Diagnosis #Transfusion ... #TRALI #TACO #Comparison
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Treated Like Acute ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin ... #differential #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes of Acute ... Hepatocellular Acute ... Cholestatic Acute ... Cirrhosis: > 1 • Acute
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