120 results
A 70 year old was presented to the urgent care center with severe retrosternal chest pain
to the urgent care ... showed a classic syndrome ... 2017-02-01p2-3/ #Clinical ... Cardiomyopathy #BrokenHeart ... #Syndrome
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... • Clinically ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... Conservative/supportive care ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... not related to clinical ... Cryoglobulins are ... Hyperviscosity syndrome ... #Rheumatology #
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... necrosis of hip (rare ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulins are ... : • Clinical triad ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... classification #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... lactam antibiotics are ... #hematology #anemia
Lemierre’s Syndrome - Clinical Presentation

97% have septic emboli to the lungs!  So look for pneumonia,
Lemierre’s Syndrome ... - Clinical Presentation ... especially if there are ... #Lemierres #Syndrome ... Signs #Symptoms #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in severe • Rare ... • Supportive Care ... Differentiation #Syndrome ... #management #hematology