15 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Destruction • Abnormal ... • Congenital - Rare ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... Conservative/supportive care ... only curative treatment ... #Management #treatment ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
+ Bleeding Treatment ... - APTT < 1.5 x normal ... #diagnosis #causes ... #treatment #management ... #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... JAK2 mutation OR Abnormally ... PolycythemiaVera #PV #Diagnosis ... #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal Individual ... multidisciplinary care ... by a hemophilia treatment ... #Management #treatment ... #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Jcortesizaguirr #Abnormal ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... amyloidosis #Abnormal ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... hemorrhage, which are ... deficiency - Abnormal ... Complete blood count coagulation ... Algorithm #Causes #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... intravascular coagulation ... #Differential #Diagnosis ... #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... 500 mg QD until normal ... • Supportive Care ... #management #hematology