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hematology management hemeonc leukemia syndrome chronic lymphocytic mds myelodysplastic algorithm anaphylaxis anesthesia anesthesiology apml checklist classification comparison differential differentiation emergencies
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... large numbers and are ... microglobulin Treatment ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphoid organs When Cancer ... Cells are in the ... transformation of the CLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... Conservative/supportive care ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... are characteristic ... Transformation to large cell ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... • Supportive Care ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... #oncology #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
severe cases) ❶ Call ... non-essential surgery. ❷ Call ... appropriate critical care ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... “big & sticky” cells ... ± tocilizumab; call ... #HemeOnc #Diagnosis
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