18 results
management oncology causes chronic clinical cll comparison differential hemeonc hemophagocytic hlh hus leukemia lymphocytic lymphohistiocytosis microangiopathy physicalexam purpura thrombocytopenia thrombocytopenic
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
) Diagnosis of ... TTP: • Rare and ... deficiency • Autoimmune ... #rheumatology # ... hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... There are primary ... . 5. 2nd TMA- autoimmune ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... transglutaminase (TTG ... Associations #diseases #diagnosis ... #table #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... , smudge cells are ... cytopenias (ITP ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... thrombocytopenic purpura (TTP ... lactam antibiotics are ... #differential #diagnosis ... #hematology #anemia
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination This 57 yo WM reported to clinic complaining of
using a cotton tip ... history of systemic autoimmune ... patient was sent to rheumatology ... systemic workup and treatment ... #physicalexam #rheumatology
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 Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Disease (AOSD) Rare ... likely conditions (autoimmune ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #treatment
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... DOACs are substrates ... Source: http://www.bloodjournal.org ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... solid cancers • Autoimmune ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
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