22 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... Conservative/supportive care ... only curative treatment ... #Management #treatment ... #hematology #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... and Management Summary ... Diagnostic Criteria ... #Management #Summary ... #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) - Summary ... minimal tumor burden Diagnosis ... , smudge cells are ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs are substrates ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... and Management Summary ... - If present, are ... life-threatening • Treatment ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... • Supportive Care ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... large numbers and are ... microglobulin Treatment ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis ... #management #treatment ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management Summary ... Clindamycin in case ... antibiotics once stable ... hemorrhage • Treatment ... shows a small, stable
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology # ... diagnosis #management