75 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Post-op surgery • Trauma ... effect following treatment ... #Causes #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... diagnosis #management #algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... infarction, Severe trauma ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... Conservative/supportive care ... only curative treatment ... #hematology #oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Solar purpura - Trauma ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Non-lmmune: • HELLP Syndrome ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... are asthma, allergy ... glucocorticoid treatment ... Differential #diagnosis #hematology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Anticoagulation (case ... by case) • Surgery ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... • Mechanical Trauma ... ) - HELLP syndrome ... lactam antibiotics are ... differential #diagnosis #hematology