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differential erythematosus lupus sle arthritis management myositis scleroderma sclerosis vasculitis arteritis autoantibodies bonetumors bony classification gca giantcell hematology hemeonc hemophagocytic
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... skin thickening Signs ... (interstitial lung ... Musculoskeletal: joint ... #diagnosis #signs
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... Internal Organs: • Joint ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... phenomenon (20%) Joints ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... heliotrope rash, Shaw sign ... , holster sign, ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... Rheumatologic Disease ... #MSK #rheumatology
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
cancerous cells from systemic ... • Lung. thvroid ... lesions that look darker ... Signs/Symptoms: ... Malignant #Radiology #Diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... day, followed by long ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... Pulmonary: Parenchymal lung ... Arthritis #RA #Signs ... #Symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatologic diseases ... Arthritis: • Joint ... Induced Lupus: • Symptoms ... #Rheumatology
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