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diagnosis hematology oncology hemeonc hemophagocytic hlh lymphohistiocytosis syndrome apml causes classification comparison differentiation heparin hit hodgkins induced lymphoma macrophage mas
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Classified among the secondary ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... complex → plt activation ... Management: • ... D/c all heparin ... #Treatment #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... Syndromes #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... the mainstay of treatment ... Systemic Fibrosis: - Secondary ... multiple myeloma or AL ... comparison #table #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #oncology #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Neutropenia - Differential ... hypertension and/or drug treatment ... drug reactions - Secondary ... Megaloblastic anemia-rare ... diagnosis #causes #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • In all patients ... STX11, STXBP2 • Secondary ... - Cytopenias (anemia ... #Hematology #HemeOnc
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... transplantation Secondary ... trigger • Almost all ... autoimmune disease, treatment ... #management #hematology
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