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differential anemia causes oncology workup classification diffuse enlarged lad lymphadenopathy macrocytic microcytic monoclonal normocytic paraproteinemias polycythemia reticulocyte spleen splenomegaly
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... - Differential Diagnosis ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... #Diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... - Differential Diagnosis ... Algorithm Decreased ... #Algorithm #Causes ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... - Differential Diagnosis ... Algorithm Low ... • Bleeding • Hemolysis ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Algorithm Infectious ... Inflammatory • Systemic ... Serum Sickness Hemolytic ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... • Systemic ... • EBV • CMV ... #Hematology #Oncology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (cell) volume (MCV ... acute blood loss, hemolysis ... #Diagnosis #Workup ... #Hematology #Microcytic
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
- Differential Diagnosis ... hyper-proliferative 2) Exclude hemolysis ... haptoglobin) 3) Use MCV ... #differential #diagnosis ... #hematology #algorithm
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Zone Lymphoma (HCV ... neuropathy) • Systemic ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... frequently affected systems ... heme (bleeding), CV ... Better call hematology ... #hematology
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