45 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
Bulge Sign to demonstrate a Knee Effusion on Physical Examination

Dr. Janet Pope @Janetbirdope

#Bulge #Sign #Knee #Effusion
Bulge Sign to demonstrate ... a Knee Effusion ... Janetbirdope #Bulge ... #PhysicalExam # ... #orthopedics #rheumatology
The Bulge Sign in Knee Effusion

Highly specific sign for knee joint effusion. 
 - Stroke the
The Bulge Sign in ... observe for a “bulge ... TBHMedicine #Bulge ... clinical #video #physicalexam ... orthopedics #sports #rheumatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... for Anemia (Morphological ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Osteoarthritis - Overuse syndrome ... Seronegative Reactive Syndrome ... #differential #diagnosis ... #msk #physicalexam
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #hematology #hemolysis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #Differential #Diagnosis
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
- Differential Diagnosis ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... #Differential #Diagnosis ... #Hematology