33 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... , Shaw sign, holster ... anti-synthetase syndrome ... after 2 years of treatment ... #diagnosis #rheumatology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... Skin-homing T-cells #Diagnosis ... #Dermatology #Rash ... Nikolsky #Algorithm #Differential
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... New-onset fever with rash ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
, the differential ... and toxic shock syndrome ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... , but without treatment ... the latent and late ... #Diagnosis #Clinical ... #Photo #Dermatology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Approach to the Rash ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... #oncology #differential ... #diagnosis #cancer
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... proliferation rate ... #TLS #diagnosis ... #management #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... anemia 4% - Myositis ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... Hospital of Baltimore IM ... #dermatology #diagnosis