13 results
Evaluation of Lymphadenopathy - Localized vs Generalized #Diagnosis #EM #IM #Honc #Lymphadenopathy #Localized #Generalized #Infectious #Malignancy
Diagnosis #EM #IM ... Infectious #Malignancy #Differential ... #Algorithm #Ddxof ... #Oncology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... epidermal turnover rate ... #Diagnosis #Dermatology ... Nikolsky #Algorithm #Differential ... #Ddxof
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
- Pathophysiology ... red-flags to exclude dermatologic ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential ... #Ddxof
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Algorithm and Differential ... Diagnosis #EM #IM ... #Urology #Hematuria ... #Macroscopic #Differential ... #Algorithm #Ddxof
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... - Differential ... of breath • Neurologic ... • Paraplegia (late ... #differential #
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential ... #Ddxof
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... #Diagnosis #hematology ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology