9 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndrome ->Cord ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... hypercoagulable states ... MCTD, Sjogren syndrome ... #diagnosis #neurology ... differential #algorithm
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
peaks between the ages ... monophasic Pathophysiology ... Hyperreflexia develops later ... Bilateral signs and/or symptoms ... diagnosis #management #neurology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... tissue => Years later ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... #staging #msk
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... the tuberculoma (later ... stage) • Headache
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... pattern of spread, B symptoms ... very high mitotic rate ... Amy Chung, MD, MSc ... Classification #pathophysiology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... impairment, Mood disorder ... (Spinal cord predominant ... objective evidence of neurologic ... diagnosis #management #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... CNS in the early stages ... • Depressive symptoms ... The clinical syndrome ... dementia #AIDS #Neurology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... or the spinal cord ... Nerve Palsies • Disordered ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms