20 results
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
of lumbosacral joint ... length due to tight ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... = Worry about late ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... phenomenon (20%) Joints ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... arthritis • SLE ... #MSK #rheumatology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
joints • Asymmetrical ... spinal column) • Late ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs ... #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Severe, worse at night ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... #signs #stages ... #staging #msk
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... proliferation rate ... Syndrome #TLS #diagnosis ... #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
costovertebral joints ... the sacroiliac joints ... #Scoliosis #pathophysiology ... #msk #diagnosis ... #signs #symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... splenomegaly), night ... Fevers • Drenching night ... #Leukemia #Hematology ... #Oncology #Diagnosis