15 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... ONCOLOGIC EMERGENCIES ... of breath • Neurologic ... • Paraplegia (late
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... deposition disease (light ... Differential #Diagnosis #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
infiltration • Light ... change disease • Hematologic ... #AKI #Cancer #Oncology ... Classification #Nephrology
Marcus Gunn Pupil - Relative Afferent Pupillary Defect (RAPD)
Definition: Afferent loop of the pupillary light reflex
the pupillary light ... neuritis due to MS ... Later (1959), Levitan ... with the swinging light ... #Defect #RAPD #neurology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... amyloidosis • Rate ... #Significance #hematology ... #diagnosis #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
very high mitotic rate ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
proprioception, and light ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... • Crystalline: light ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Increase => Months later ... tissue => Years later ... Severe, worse at night ... FrozenShoulder #pathophysiology ... stages #staging #msk